HOW DISEASE IS SPREAD.

How Much Improvement is Expected in Ocular Lesions of Behçet's Disease Treated with Pulse Cyclophosphamide?

Background: The natural history of ocular lesions in Behçet's disease is toward severe loss of vision/blindness in few years, whereas cytotoxic drugs have changed the outcome. Several open labeled cohort studies showed pulse cyclophosphamide (PCP) to be the best choice. Since one third of these patients are resistant to PCP it is important to know how much improvement one can expect from the r...

How much "spread" in AWP pricing is unlawful?

A colorful ruling by federal U.S. District Court Judge Patti B. Saris (Boston) dated June 21, 2007, proclaimed that some pharmaceutical manufacturers had been “unscrupulously taking advantage of the flawed AWP (average wholesale price) system . . . by establishing secret mega-spreads far beyond the standard industry markup,” describing this behavior as “unethical and oppressive.” The case invol...

Understanding how Twitter is used to spread scientific messages∗

According to a survey we recently conducted, Twitter was ranked in the top three services used by Semantic Web researchers to spread information. In order to understand how Twitter is practically used for spreading scientific messages, we captured tweets containing the official hashtags of three conferences and studied (1) the type of content that researchers are more likely to tweet, (2) how t...

How is the Mother Tongue Acquired

Platelet Refractoriness and how it is formed

Abstract Background and Objectives Transfusion of platelet has become one of the main treatments for thrombocytopenic patients to reduce the severity and frequency of bleeding consequences. Failure to attain the desired level of platelets in a patient following platelet transfusion is defined as platelet refractoriness. The purpose of present paper is to review and study the mechanisms involve...